The Reaction of Various Functional Systems of the Body in the Dynamics of Oxygen Deficiency

Marietta Karapetyan; Nonna Adamyan; Susanna Sahakyan

doi:doi:10.11648/j.ajbio.20221002.18

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The Reaction of Various Functional Systems of the Body in the Dynamics of Oxygen Deficiency

Marietta Karapetyan, Nonna Adamyan, Susanna Sahakyan

Published in American Journal of BioScience (Volume 10, Issue 2)

Received: 19 March 2022 Accepted: 9 April 2022 Published: 28 April 2022

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Abstract

The paper presents a comparative analysis of data on the effect of moderate and acute hypoxia on the functional state of systems at various levels of organization - molecular (amide groups of brain proteins), cellular (background electrical activity of neurons), systemic (electroencephalogram - EEG, electrocardiogram (ECG) and organismic (integrative signal of the body). Changes in electrographic parameters have an adaptive meaning for the body and are of a phase nature: in moderate hypoxia (4500-5000 m) the indicators are activated, and at acute hypoxia (7500 - 8000 m) - are depressed. 15-30 minutes after exposure to hypoxia at normal atmospheric pressure, the values of almost all indicators are back to normal. It is shown, that a prolonged aftereffect of acute hypoxia is observed at the organism molecular level. Under oxygen deficiency, the number of amide groups of brain proteins increases. After the hypoxic factor, this violation persists for a day. The data of the influence of hypoxia on animals, lead to the conclusion, that the functional systems of different levels of organization react ambiguously to the impact of increasing oxygen deficiency. However, in the dynamics of hypoxia in the values of the integrative signal recorded by a non-invasive method from the body surface, phase changes are not observed, on the contrary, the shifts are unidirectional. Certain deviations of the indicators of the integrative signal in the phase of moderate hypoxia increase during acute hypoxia and continue for several hours. We conclude that the remote "Bioscope" signal being integral in nature, is not the sum of individual electrographic indicators of various functional systems and has a high sensitivity and specificity to the change of physiological state of animal.

Published in	American Journal of BioScience (Volume 10, Issue 2)
DOI	10.11648/j.ajbio.20221002.18
Page(s)	89-93
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Oxygen Deficiency, Neuronal Activity, Electroencephalogram (EEG), Electrocardiogram (ECG), Integrative Field, Brain Proteins

References

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APA Style

Marietta Karapetyan, Nonna Adamyan, Susanna Sahakyan. (2022). The Reaction of Various Functional Systems of the Body in the Dynamics of Oxygen Deficiency. American Journal of BioScience, 10(2), 89-93. https://doi.org/10.11648/j.ajbio.20221002.18

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ACS Style

Marietta Karapetyan; Nonna Adamyan; Susanna Sahakyan. The Reaction of Various Functional Systems of the Body in the Dynamics of Oxygen Deficiency. Am. J. BioScience 2022, 10(2), 89-93. doi: 10.11648/j.ajbio.20221002.18

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AMA Style

Marietta Karapetyan, Nonna Adamyan, Susanna Sahakyan. The Reaction of Various Functional Systems of the Body in the Dynamics of Oxygen Deficiency. Am J BioScience. 2022;10(2):89-93. doi: 10.11648/j.ajbio.20221002.18

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@article{10.11648/j.ajbio.20221002.18,
  author = {Marietta Karapetyan and Nonna Adamyan and Susanna Sahakyan},
  title = {The Reaction of Various Functional Systems of the Body in the Dynamics of Oxygen Deficiency},
  journal = {American Journal of BioScience},
  volume = {10},
  number = {2},
  pages = {89-93},
  doi = {10.11648/j.ajbio.20221002.18},
  url = {https://doi.org/10.11648/j.ajbio.20221002.18},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbio.20221002.18},
  abstract = {The paper presents a comparative analysis of data on the effect of moderate and acute hypoxia on the functional state of systems at various levels of organization - molecular (amide groups of brain proteins), cellular (background electrical activity of neurons), systemic (electroencephalogram - EEG, electrocardiogram (ECG) and organismic (integrative signal of the body). Changes in electrographic parameters have an adaptive meaning for the body and are of a phase nature: in moderate hypoxia (4500-5000 m) the indicators are activated, and at acute hypoxia (7500 - 8000 m) - are depressed. 15-30 minutes after exposure to hypoxia at normal atmospheric pressure, the values of almost all indicators are back to normal. It is shown, that a prolonged aftereffect of acute hypoxia is observed at the organism molecular level. Under oxygen deficiency, the number of amide groups of brain proteins increases. After the hypoxic factor, this violation persists for a day. The data of the influence of hypoxia on animals, lead to the conclusion, that the functional systems of different levels of organization react ambiguously to the impact of increasing oxygen deficiency. However, in the dynamics of hypoxia in the values of the integrative signal recorded by a non-invasive method from the body surface, phase changes are not observed, on the contrary, the shifts are unidirectional. Certain deviations of the indicators of the integrative signal in the phase of moderate hypoxia increase during acute hypoxia and continue for several hours. We conclude that the remote "Bioscope" signal being integral in nature, is not the sum of individual electrographic indicators of various functional systems and has a high sensitivity and specificity to the change of physiological state of animal.},
 year = {2022}
}

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TY  - JOUR
T1  - The Reaction of Various Functional Systems of the Body in the Dynamics of Oxygen Deficiency
AU  - Marietta Karapetyan
AU  - Nonna Adamyan
AU  - Susanna Sahakyan
Y1  - 2022/04/28
PY  - 2022
N1  - https://doi.org/10.11648/j.ajbio.20221002.18
DO  - 10.11648/j.ajbio.20221002.18
T2  - American Journal of BioScience
JF  - American Journal of BioScience
JO  - American Journal of BioScience
SP  - 89
EP  - 93
PB  - Science Publishing Group
SN  - 2330-0167
UR  - https://doi.org/10.11648/j.ajbio.20221002.18
AB  - The paper presents a comparative analysis of data on the effect of moderate and acute hypoxia on the functional state of systems at various levels of organization - molecular (amide groups of brain proteins), cellular (background electrical activity of neurons), systemic (electroencephalogram - EEG, electrocardiogram (ECG) and organismic (integrative signal of the body). Changes in electrographic parameters have an adaptive meaning for the body and are of a phase nature: in moderate hypoxia (4500-5000 m) the indicators are activated, and at acute hypoxia (7500 - 8000 m) - are depressed. 15-30 minutes after exposure to hypoxia at normal atmospheric pressure, the values of almost all indicators are back to normal. It is shown, that a prolonged aftereffect of acute hypoxia is observed at the organism molecular level. Under oxygen deficiency, the number of amide groups of brain proteins increases. After the hypoxic factor, this violation persists for a day. The data of the influence of hypoxia on animals, lead to the conclusion, that the functional systems of different levels of organization react ambiguously to the impact of increasing oxygen deficiency. However, in the dynamics of hypoxia in the values of the integrative signal recorded by a non-invasive method from the body surface, phase changes are not observed, on the contrary, the shifts are unidirectional. Certain deviations of the indicators of the integrative signal in the phase of moderate hypoxia increase during acute hypoxia and continue for several hours. We conclude that the remote "Bioscope" signal being integral in nature, is not the sum of individual electrographic indicators of various functional systems and has a high sensitivity and specificity to the change of physiological state of animal.
VL  - 10
IS  - 2
ER  -

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Author Information

Marietta Karapetyan

Department of Human and Animal Physiology, Faculty of Biology, Yerevan State University, Yerevan, Armenia
Nonna Adamyan

Department of Human and Animal Physiology, Faculty of Biology, Yerevan State University, Yerevan, Armenia
Susanna Sahakyan

Department of Human and Animal Physiology, Faculty of Biology, Yerevan State University, Yerevan, Armenia

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APA Style

Marietta Karapetyan, Nonna Adamyan, Susanna Sahakyan. (2022). The Reaction of Various Functional Systems of the Body in the Dynamics of Oxygen Deficiency. American Journal of BioScience, 10(2), 89-93. https://doi.org/10.11648/j.ajbio.20221002.18

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ACS Style

Marietta Karapetyan; Nonna Adamyan; Susanna Sahakyan. The Reaction of Various Functional Systems of the Body in the Dynamics of Oxygen Deficiency. Am. J. BioScience 2022, 10(2), 89-93. doi: 10.11648/j.ajbio.20221002.18

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AMA Style

Marietta Karapetyan, Nonna Adamyan, Susanna Sahakyan. The Reaction of Various Functional Systems of the Body in the Dynamics of Oxygen Deficiency. Am J BioScience. 2022;10(2):89-93. doi: 10.11648/j.ajbio.20221002.18

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@article{10.11648/j.ajbio.20221002.18,
  author = {Marietta Karapetyan and Nonna Adamyan and Susanna Sahakyan},
  title = {The Reaction of Various Functional Systems of the Body in the Dynamics of Oxygen Deficiency},
  journal = {American Journal of BioScience},
  volume = {10},
  number = {2},
  pages = {89-93},
  doi = {10.11648/j.ajbio.20221002.18},
  url = {https://doi.org/10.11648/j.ajbio.20221002.18},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbio.20221002.18},
  abstract = {The paper presents a comparative analysis of data on the effect of moderate and acute hypoxia on the functional state of systems at various levels of organization - molecular (amide groups of brain proteins), cellular (background electrical activity of neurons), systemic (electroencephalogram - EEG, electrocardiogram (ECG) and organismic (integrative signal of the body). Changes in electrographic parameters have an adaptive meaning for the body and are of a phase nature: in moderate hypoxia (4500-5000 m) the indicators are activated, and at acute hypoxia (7500 - 8000 m) - are depressed. 15-30 minutes after exposure to hypoxia at normal atmospheric pressure, the values of almost all indicators are back to normal. It is shown, that a prolonged aftereffect of acute hypoxia is observed at the organism molecular level. Under oxygen deficiency, the number of amide groups of brain proteins increases. After the hypoxic factor, this violation persists for a day. The data of the influence of hypoxia on animals, lead to the conclusion, that the functional systems of different levels of organization react ambiguously to the impact of increasing oxygen deficiency. However, in the dynamics of hypoxia in the values of the integrative signal recorded by a non-invasive method from the body surface, phase changes are not observed, on the contrary, the shifts are unidirectional. Certain deviations of the indicators of the integrative signal in the phase of moderate hypoxia increase during acute hypoxia and continue for several hours. We conclude that the remote "Bioscope" signal being integral in nature, is not the sum of individual electrographic indicators of various functional systems and has a high sensitivity and specificity to the change of physiological state of animal.},
 year = {2022}
}

Copy | Download

TY  - JOUR
T1  - The Reaction of Various Functional Systems of the Body in the Dynamics of Oxygen Deficiency
AU  - Marietta Karapetyan
AU  - Nonna Adamyan
AU  - Susanna Sahakyan
Y1  - 2022/04/28
PY  - 2022
N1  - https://doi.org/10.11648/j.ajbio.20221002.18
DO  - 10.11648/j.ajbio.20221002.18
T2  - American Journal of BioScience
JF  - American Journal of BioScience
JO  - American Journal of BioScience
SP  - 89
EP  - 93
PB  - Science Publishing Group
SN  - 2330-0167
UR  - https://doi.org/10.11648/j.ajbio.20221002.18
AB  - The paper presents a comparative analysis of data on the effect of moderate and acute hypoxia on the functional state of systems at various levels of organization - molecular (amide groups of brain proteins), cellular (background electrical activity of neurons), systemic (electroencephalogram - EEG, electrocardiogram (ECG) and organismic (integrative signal of the body). Changes in electrographic parameters have an adaptive meaning for the body and are of a phase nature: in moderate hypoxia (4500-5000 m) the indicators are activated, and at acute hypoxia (7500 - 8000 m) - are depressed. 15-30 minutes after exposure to hypoxia at normal atmospheric pressure, the values of almost all indicators are back to normal. It is shown, that a prolonged aftereffect of acute hypoxia is observed at the organism molecular level. Under oxygen deficiency, the number of amide groups of brain proteins increases. After the hypoxic factor, this violation persists for a day. The data of the influence of hypoxia on animals, lead to the conclusion, that the functional systems of different levels of organization react ambiguously to the impact of increasing oxygen deficiency. However, in the dynamics of hypoxia in the values of the integrative signal recorded by a non-invasive method from the body surface, phase changes are not observed, on the contrary, the shifts are unidirectional. Certain deviations of the indicators of the integrative signal in the phase of moderate hypoxia increase during acute hypoxia and continue for several hours. We conclude that the remote "Bioscope" signal being integral in nature, is not the sum of individual electrographic indicators of various functional systems and has a high sensitivity and specificity to the change of physiological state of animal.
VL  - 10
IS  - 2
ER  -

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